OUR CONTRACT PHARMACEUTICAL SERVICES

Company Overview

PARTICLE SIZE REDUCTION TECHNOLOGY

Where drugs exhibit reduced bioavailability due to poor solubility, the cause is often intrinsically linked with particle size.

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Reducing the particle size increases the surface area for a given volume, and may immediately produce improvements in solubility and the rate of dissolution. Both factors will potentially increase bioavailability.

There are several strategies and delivery technologies that use particle size reduction as a route to successful dosage formulation, and we have working partnerships with a number of companies who specialise in reducing particle size in APIs and providing the associated analytical services.

Solubility & Bioavailability

pH Control

Adjustment of the pH value for increasing the water solubility of ionisable compounds.

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Particle Size Reduction

Where drugs exhibit reduced bioavailability due to poor solubility, the cause is often intrinsically linked with particle size.

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Solid Dispersions

Solid dispersions work by dispersing the poorly-soluble drug within a highly soluble solid hydrophilic matrix.

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Lipophilic Systems

Highly experienced in identifying the most suitable lipid excipients for the challenges of dispersion, dissolution or digestion

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Let's Talk Project Success

Talk directly to the Quay staff - Our dedicated team leaders are ready to listen and help with your project.

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